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Akt (pan) (14Z4) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM71882
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IP,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM71882
  • 别名
    AKT2;AKT3
  • 产品名称
    Akt (pan) (14Z4) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    AKT1
  • 蛋白名称
    RAC-alpha serine/threonine-protein kinase;RAC-beta serine/threonine-protein kinase;RAC-gamma serine/threonine-protein kinase
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    207;208;10000
  • Human Swissprot No.
    P31749;P31751;Q9Y243
  • Mouse Gene ID
    11651;11652;23797
  • Mouse Swissprot No.
    P31750
  • Rat Gene ID
    24185;25233;29414
  • Rat Swissprot No.
    P47196;P47197;Q63484
  • 特异性
    Endogenous
  • 稀释度
    IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
  • 参考分子量
    55kDa
  • 预测分子量
    55kDa
  • 宿主
    Rabbit
  • 同种型
    IgG,Kappa
  • 组织表达
    Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
  • 细胞定位
    Cytoplasm . Nucleus . Cell membrane . Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane where it is targeted for further phosphorylations on Thr-308 and Ser-473 leading to its activation and the activated form translocates to the nucleus. Colocalizes with WDFY2 in intracellular vesicles (PubMed:16792529).
  • 纯化
    Protein A
储存与保存

1.保存:-20℃

2.有效期:1年

注意事项

1.我司生产的生化试剂如无特殊标注,基本为非无菌包装,若用于细胞实验,请提前做好预处理。需低温保存的产品,一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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