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LC3B (19C7) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM68875
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM68875
  • 别名
    MAP1LC3B
  • 产品名称
    LC3B (19C7) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    MAP1LC3B
  • 蛋白名称
    MAP1LC3B
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    81631
  • Human Swissprot No.
    Q9GZQ8
  • Mouse Swissprot No.
    Q9CQV6
  • 稀释度
    IHC-P 1:200-1:1000, WB 1:1000-1:5000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000
  • 参考分子量
    14kDa,16kDa
  • 预测分子量
    14kDa,16kDa
  • 宿主
    Rabbit
  • 同种型
    Monoclonal, rabbit, IgG, Kappa
  • 背景介绍
    The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]
  • 功能
    caution:PubMed:12740394 has shown that the protein is cleaved at Lys-122 but PubMed:15355958 has shown that the cleavage site is at Gly-120 as in other mammalian orthologs.,function:Probably involved in formation of autophagosomal vacuoles (autophagosomes).,PTM:The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form LC3-II.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:LC3-II binds to the autophagic membranes.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.,tissue specificity:Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.
  • 纯化
    Protein A
储存与保存

1.保存:-20℃

2.有效期:1年

注意事项

1.我司生产的生化试剂如无特殊标注,基本为非无菌包装,若用于细胞实验,请提前做好预处理。需低温保存的产品,一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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