热搜词： 生化试剂 血清抗 细胞 pvdf膜 抗体

咨询热线

13564444959

产品中心

当前位置：首页 > 产品中心 > 抗体蛋白 > 一抗
产品中心
订货方式
订货电话：13564444959
订货时间：周一至周五
订货Q Q：79688691
订货邮件：79688691@qq.com
Stat6 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM55769
复制产品信息
  • 种属：H，M，Mk
  • 用途：WB，ELISA，IHC-P，IF-P，IF-F，IF-ICC
规格:
20μl 50μl 100μl
单位:
支
单价:￥800.00
产品简介
储存与保存
注意事项
产品简介
  • 货号
    IM55769
  • 别名
    STAT6; Signal transducer and activator of transcription 6; IL-4 Stat
  • 产品名称
    Stat6 Rabbit Polyclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    STAT6
  • 蛋白名称
    Signal transducer and activator of transcription 6
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 反应种属
    Human,Mouse,Monkey
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    6778
  • Human Swissprot No.
    P42226
  • Mouse Gene ID
    20852
  • Mouse Swissprot No.
    P52633
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human STAT6. AA range:608-657
  • 特异性
    Stat6 Polyclonal Antibody detects endogenous levels of Stat6 protein.
  • 稀释度
    WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:5000, IF-P/IF-F/IF-ICC 1:50-200
  • 预测分子量
    94kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
  • 组织表达
    Uterus,
  • 细胞定位
    Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • 信号通路
    Jak_STAT;
  • 功能
    unction:Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.,PTM:Tyrosine phosphorylated following stimulation by IL-4 and IL-3.,similarity:Belongs to the transcription factor STAT family.,similarity:Contains 1 SH2 domain.,subcellular location:Translocated into the nucleus in response to phosphorylation.,subunit:Forms a homodimer or a heterodimer with a related family member (By similarity). Interacts with NCOA1 via its C-terminal LXXLL motif.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃

2.有效期：1年

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

备注：由于产品信息可能会有优化升级，请以实际收货标签信息为准。

产品推荐
<