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Podoplanin (4Z6) Mouse Monoclonal Antibody  Cite:0    分享

货号： IMP1027
复制产品信息
  • 种属：H
  • 用途：WB，ELISA，IHC-P
规格:
50μl 100μl
单位:
支
单价:￥1800.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Podoplanin (4Z6) Mouse Monoclonal Antibody
  • 别名
    Podoplanin (Aggrus) (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1-alpha) (T1A);GP36;PSEC0003;PSEC0025
  • 类别
    抗体产品
  • 基因名称
    PDPN
  • 蛋白名称
    Aggrus Glycoprotein 36 Gp36 PA2.26 antigen T1-alpha T1A
  • 推荐应用
    IHC-P,mIHC,ELISA
  • 稀释度
    IHC-P/mIHC 1:50-200. ELISA 1:500-5000
  • 反应种属
    Human
  • 制备方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 存储缓冲液
    PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
  • Human Swissprot No.
    Q86YL7
  • Mouse Swissprot No.
    Q62011
  • Rat Swissprot No.
    Q64294
  • 特异性
    The antibody can specifically recognize human Podoplanin protein. In western blotting of U2O2 cell lysate, the antibody can label a 36 kDa band corresponding to Podoplanin.
  • 预测分子量
    18kD
  • 组织表达
    Tonsil/ Appendix
  • 细胞定位
    Cytoplasmic
  • 功能
    caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.,PTM:Extensively O-glycosylated. Contains sialic acid residues. O-glycosylation is necessary for platelet aggregation activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the podoplanin family.,subcellular location:Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles.,tissue specificity:Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.,
  • 纯化
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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