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MTCO2 (15J19) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM68946
复制产品信息
  • 种属:H
  • 用途:WB,ELISA,IP,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM68946
  • 别名
    COII;COXII;MTCO2
  • 产品名称
    MTCO2 (15J19) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    MT-CO2
  • 蛋白名称
    Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
  • 反应种属
    Human
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    4513
  • Human Swissprot No.
    P00403
  • Mouse Swissprot No.
    P00405
  • Rat Swissprot No.
    P00406
  • 稀释度
    IHC-P 1:200-1000,WB 1:1000-5000,IF-P/IF-F/IF-ICC 1:200-1000,ELISA 1:5000-20000,IP 1:50-200
  • 参考分子量
    21kDa
  • 预测分子量
    26kDa
  • 宿主
    Rabbit
  • 同种型
    Monoclonal, rabbit, IgG, Kappa
  • 背景介绍
    cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.
  • 信号通路
    Oxidative phosphorylation;Cardiac muscle contraction;Alzheimer's disease;Parkinson's disease;Huntington's disease.
  • 功能
    cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.
  • 纯化
    Protein A
储存与保存

1.保存:-20℃

2.有效期:1年

注意事项

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