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COX2 (6A9) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM68883
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM68883
  • 别名
    COX2
  • 产品名称
    COX2 (6A9) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    PTGS2
  • 蛋白名称
    Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    5743
  • Human Swissprot No.
    P35354
  • 稀释度
    IHC-P 1:100-1:500, WB 1:1000-1:5000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000
  • 参考分子量
    75kDa
  • 预测分子量
    69kDa
  • 宿主
    Rabbit
  • 同种型
    Monoclonal, rabbit, IgG, Kappa
  • 背景介绍
    Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009].
  • 功能
    catalytic activity:Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group per subunit.,disease:Likely to play a role in inflammatory diseases such as rheumatoid arthritis.,function:May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.,induction:By cytokines and mitogens.,miscellaneous:This enzyme acts both as a dioxygenase and as a peroxidase.,miscellaneous:This enzyme is the target of nonsteroidal anti-inflammatory drugs such as aspirin.,pathway:Lipid metabolism; prostaglandin biosynthesis.,similarity:Belongs to the prostaglandin G/H synthase family.,similarity:Contains 1 EGF-like domain.,subunit:Homodimer.
  • 纯化
    Protein A
储存与保存

1.保存:-20℃

2.有效期:1年

注意事项

1.我司生产的生化试剂如无特殊标注,基本为非无菌包装,若用于细胞实验,请提前做好预处理。需低温保存的产品,一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

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4.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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