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LYVE1 (2A12) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM68738
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
支
单价:¥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    RM8064
  • 别名
    CRSBP1;HAR;XLKD1;UNQ230/PRO263
  • 产品名称
    LYVE1 (2A12) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    LYVE1
  • 蛋白名称
    Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1) (Hyaluronic acid receptor)
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    10894
  • Human Swissprot No.
    Q9Y5Y7
  • Mouse Swissprot No.
    Q8BHC0
  • 稀释度
    IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000
  • 参考分子量
    35kDa
  • 预测分子量
    35kDa
  • 宿主
    Rabbit
  • 同种型
    Monoclonal, rabbit, IgG, Kappa
  • 背景介绍
    This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008].
  • 功能
    function:Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.,PTM:O-glycosylated.,similarity:Contains 1 Link domain.,subcellular location:Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.,subunit:Homodimer; disulfide-linked. Interacts with PDGFB and IGFBP3. Forms a transient ternary complex with PDGFB and PDGFRB in TGN.,tissue specificity:Mainly expressed in endothelial cells lining lymphatic vessels.
  • 纯化
    Protein A
储存与保存

1.保存:-20℃

2.有效期:1年

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