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SFRP1 (1U15) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM35215
复制产品信息
  • 种属：H，M，R
  • 用途：WB，FCM，IP
规格:
50µl 100µl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    SFRP1 (1U15) Rabbit Monoclonal Antibody
  • 别名
    Frizzled related protein 1; FRP1; FrzA; SARP2; Secreted apoptosis related protein 2; Secreted frizzled related protein 1; SFRP1;
  • 类别
    抗体产品
  • 基因名称
    SFRP1
  • 蛋白名称
    FRP, FRP1, SARP2
  • Clonality
    Monoclonal
  • 推荐应用
    WB,FCM,IP
  • 稀释度
    WB 1:1000, FCM 1:200-1:500, IP 1:20-1:50
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID
    6422
  • Human Swissprot No.
    Q8N474
  • 免疫原
    Recombinant protein of human SFRP1
  • 参考分子量
    35kDa
  • 预测分子量
    35kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 组织表达
    Widely expressed. Absent from lung, liver and peripheral blood leukocytes. Highest levels in heart and fetal kidney Also expressed in testis, ovary, fetal brain and lung, leiomyomal cells, myometrial cells and vascular smooth muscle cells. Expressed in foreskin fibroblasts and in keratinocytes
  • 细胞定位
    Secreted. Note=Cell membrane or extracellular matrix-associated. Released by heparin-binding
  • 功能
    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF- dependent transcription.
  • 纯化
    Affinity-chromatography
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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