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RPA32 (10E8) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM40004
复制产品信息
  • 种属：H
  • 用途：WB，FCM，IP，IHC-P，IF-P，IF-ICC
规格:
50µl 100µl
单位:
支
单价:￥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM40004
  • Uniprot ID
    P15927
  • Gene ID
    6118
  • 别名
    REPA2; RPA32; RP-A p32; RP-A p34
  • 产品名称
    RPA32 (10E8) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-ICC,FCM,IP,IF-P
  • 反应种属
    Human
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • 免疫原
    Recombinant protein of human RPA32/RPA2
  • 稀释度
    WB 1:1000, IHC-P/IF-P 1:1000-1:5000, IF-ICC 1:100, FCM 1:200-1:500, IP 1:20-1:50
  • 参考分子量
    29kDa
  • 预测分子量
    29kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 背景介绍
    This gene encodes a subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, recombination, telomere maintenance, and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase. The RPA complex protects single-stranded DNA from nucleases, prevents formation of secondary structures that would interfere with repair, and co-ordinates the recruitment and departure of different genome maintenance factors. The heterotrimeric complex has two different modes of ssDNA binding, a low-affinity and high-affinity mode, determined by which oligonucleotide/oligosaccharide-binding (OB) domains of the complex are utilized, and differing in the length of DNA bound. This subunit contains a single OB domain that participates in high-affinity DNA binding and also contains a winged helix domain at its carboxy terminus, which interacts with many genome maintenance protein. Post-translational modifications of the RPA complex also plays a role in co-ordinating different damage response pathways. [provided by RefSeq, Sep 2017]
  • 纯化
    Affinity Purification
储存与保存

1.保存：-20℃

2.有效期：1年

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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