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IP Receptor Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM54015
复制产品信息
  • 种属：H，M，R
  • 用途：WB，ELISA，IHC-P
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    IP Receptor Rabbit Polyclonal Antibody
  • 别名
    PTGIR; PRIPR; Prostacyclin receptor; Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor
  • 类别
    抗体产品
  • 基因名称
    PTGIR
  • 蛋白名称
    Prostacyclin receptor
  • Clonality
    Polyclonal
  • 推荐应用
    WB,ELISA,IHC-P
  • 稀释度
    WB 1:500-2000, IHC-P 1:50-300, ELISA 2000-20000
  • 反应种属
    Human,Rat,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    5739
  • Human Swissprot No.
    P43119
  • Mouse Swissprot No.
    P43252
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human Prostacyclin Receptor. AA range:198-247
  • 特异性
    IP Receptor Polyclonal Antibody detects endogenous levels of IP Receptor protein.
  • 预测分子量
    45kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008],
  • 组织表达
    Lung,Pancreas,Placenta
  • 细胞定位
    Cell membrane; Multi-pass membrane protein.
  • 信号通路
    Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction;
  • 功能
    function:Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.,PTM:Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.,PTM:Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling.,similarity:Belongs to the G-protein coupled receptor 1 family.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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