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Claudin-2 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM52823
复制产品信息
  • 种属：H，M
  • 用途：WB，ELISA，IHC-P，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Claudin-2 Rabbit Polyclonal Antibody
  • 别名
    CLDN2; PSEC0059; SP82; Claudin-2; SP82
  • 类别
    抗体产品
  • 基因名称
    CLDN2
  • 蛋白名称
    Claudin-2
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:5000, IF-P/IF-F/IF-ICC 1:50-200
  • 反应种属
    Human,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    9075
  • Human Swissprot No.
    P57739
  • Mouse Gene ID
    12738
  • Mouse Swissprot No.
    O88552
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human Claudin 2. AA range:181-230
  • 特异性
    Claudin-2 Polyclonal Antibody detects endogenous levels of Claudin-2 protein.
  • 预测分子量
    25kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010],
  • 组织表达
    Colon,Colon epithelium,Kidney,Skin,Teratocarcinoma,Thalamus,
  • 细胞定位
    Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .
  • 信号通路
    Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;
  • 功能
    function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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