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AQP1 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM52265
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  • 种属：H，M，R
  • 用途：WB，ELISA
规格:
50μl 100μl
单位:
支
单价:￥1200.00
产品简介
储存与保存
注意事项
产品简介
  • 货号
    IM52265
  • 别名
    AQP1; CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
  • 产品名称
    AQP1 Rabbit Polyclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    AQP1
  • 蛋白名称
    Aquaporin-1
  • Clonality
    Polyclonal
  • 推荐应用
    WB,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    358
  • Human Swissprot No.
    P29972
  • Mouse Gene ID
    11826
  • Mouse Swissprot No.
    Q02013
  • Rat Gene ID
    25240
  • Rat Swissprot No.
    P29975
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human AQP1. AA range:101-150
  • 特异性
    AQP1 Polyclonal Antibody detects endogenous levels of AQP1 protein.
  • 稀释度
    WB 1:500-1:2000, ELISA 1:40000.Not yet tested in other applications.
  • 预测分子量
    29kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement. [provided by RefSeq, Aug 2016],
  • 组织表达
    Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
  • 细胞定位
    Cell membrane ; Multi-pass membrane protein .
  • 功能
    domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.,miscellaneous:Pharmacologically inhibited by submillimolar concentrations of mercury.,online information:Blood group antigen gene mutation database,online information:Liquid states - Issue 36 of July 2003,polymorphism:AQP1 is responsible for the Colton blood group system. Approximately 92% of Caucasians are Co(A+B-) (Ala-46), approximately 8% are Co(A+B+), and only 0.2% are Co(A-B+) (Val-46). Co(A-B-) which is very rare, is due to a complete absence of AQP1.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,subunit:Homotetramer.,tissue specificity:Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃

2.有效期：1年


注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

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