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SLC40A1 Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM68457
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  • 种属:H,M,R
  • 用途:WB
规格:
50μl 100μl
单位:
单价:¥1100.00
基本信息
注意事项
基本信息
  • 产品货号
    IM68457
  • 产品名称
    SLC40A1 Rabbit Polyclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    SLC40A1 FPN1 IREG1 SLC11A3 MSTP079
  • 蛋白名称
    Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1)
  • Clonality
    Polyclonal
  • 推荐应用
    WB
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 制备方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    30061
  • Human Swissprot No.
    Q9NP59
  • Mouse Gene ID
    53945
  • Mouse Swissprot No.
    Q9JHI9
  • Rat Gene ID
    170840
  • Rat Swissprot No.
    Q923U9
  • 特异性
    This antibody detects endogenous levels of SLC40A1 at Human, Mouse,Rat
  • 稀释度
    WB 1:500-2000
  • 预测分子量
    63kDa
  • 运输及保存条件
    -15°C to -25°C/1 year(Do not lower than -25°C)
  • 组织表达
    Detected in erythrocytes (at protein level). Expressed in placenta, intestine, muscle and spleen.
  • 细胞定位
    Cell membrane ; Multi-pass membrane protein . Localized to the basolateral membrane of polarized epithelial cells.
  • 功能
    Major iron transporter that plays a key role in balancing cellular and systemic iron levels . Transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages, and release of iron stores in hepatocytes (By similarity). When iron is in excess, hepcidin/HAMP levels increase resulting in a degradation of ferroportin/SLC40A1 limiting the iron efflux to plasma .
注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

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