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PPIL2 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM66686
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  • 种属：H，M
  • 用途：WB
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    PPIL2 Rabbit Polyclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    PPIL2
  • 蛋白名称
    Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 5.2.1.8) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Rotamase PPIL2)
  • Clonality
    Polyclonal
  • 推荐应用
    WB
  • 稀释度
    WB 1:500-2000
  • 反应种属
    Human,Mouse
  • 浓度
    1 mg/ml
  • 制备方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    23759
  • Human Swissprot No.
    Q13356
  • Mouse Gene ID
    66053
  • Mouse Swissprot No.
    Q9D787
  • 特异性
    This antibody detects endogenous levels of PPIL2 at Human, Mouse
  • 预测分子量
    57kDa
  • 宿主
    Rabbit
  • 组织表达
    Highest expression in thymus, pancreas and testis. Also detected in heart, placenta, lung, liver, skeletal muscle, kidney, spleen, prostate, ovary, small intestine and colon. Poorly detected in brain and leukocytes. Strong protein expression in lymph node (cortical, paracortical and medullar regions), thyroid (follicular epithelial cells), testis (developing spermatozoa), stomach (cells lining the gastric pit), pancreas, kidney (proximal and distal-tubule cells and collecting duct cells but not in glomeruli), endometrium and colon (goblet cells). Moderate protein expression in spleen, prostate (epithelium and squamous cell carcinomas), placenta and adrenal gland. Weak protein expression in liver, heart, breast, ovary, and lung. No protein expression in brain and bladder. High protein expression in most lymphomas and melanomas.
  • 细胞定位
    Nucleus . May also localize to the cytoplasm and the cell membrane. .
  • 功能
    Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation . May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance . Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity .
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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