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Bcl-XL (6X17) Mouse Monoclonal antibody  Cite:0    分享

货号： IM46153
复制产品信息
  • 种属：H，M，R
  • 用途：WB，IHC-P，IF-P，IF-F，IF-ICC，IHC-F
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Bcl-XL (6X17) Mouse Monoclonal antibody
  • 类别
    抗体产品
  • 基因名称
    BCL2L1
  • Clonality
    Monoclonal
  • 推荐应用
    IF-P,IF-F,IF-ICC,IHC-P,IHC-F,WB
  • 稀释度
    WB 1:200-1:1000, IF-P/IF-F/IF-ICC 1:100
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
  • Uniprot ID
    Q07817
  • Gene ID
    NM_138578
  • 免疫原
    Recombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL
  • 预测分子量
    25.9kDa
  • 宿主
    Mouse
  • 同种型
    IgG2a
  • 背景介绍
    Bcl-XL belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator
  • 纯化
    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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