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Notch1 (4N16) Mouse Monoclonal antibody  Cite:0    分享

货号： IM45013
复制产品信息
  • 种属：H，M，R
  • 用途：WB，IHC-P，IHC-F
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Notch1 (4N16) Mouse Monoclonal antibody
  • 类别
    抗体产品
  • 基因名称
    NOTCH1
  • Clonality
    Monoclonal
  • 推荐应用
    IHC-P,IHC-F,WB
  • 稀释度
    WB 1:1000, IHC-P/IHC-F 1:50-1:150
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
  • 免疫原
    Recombinant protein expressed in E.coli corresponding to amino acids 2300-2556 of human NOTCH1
  • 预测分子量
    270.6kDa
  • 宿主
    Mouse
  • 同种型
    IgG2b
  • 背景介绍
    Notch1 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development
  • 纯化
    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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