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K48-linkage Specific Ubiquitin (15X11) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM34924
复制产品信息
  • 种属：H，M，R
  • 用途：WB，FCM，IHC-P，IF-P，IF-ICC
规格:
50µl 100µl
单位:
支
单价:￥1200.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM34924
  • 别名
    FLJ25987; MGC8385; ubiquitin B; Ubiquitin; UBCEP1; UBCEP2; RPS27A;
  • 产品名称
    K48-linkage Specific Ubiquitin (15X11) Rabbit Monoclonal Antibody
  • 类别
    抗原抗体
  • 基因名称
    UBB
  • Clonlity
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-ICC,FCM,IF-P
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Humn Gene ID
    7314
  • 免疫原
    A synthetic peptide of human K-48 Linkage Specific Ubiquitin
  • 稀释度
    WB 1:1000, IHC-P/IF-P 1:200, IF-ICC 1:200-1:500, FCM 1:20
  • 预测分子量
    26kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 注意事项
    K48-linkage Specific Ubiquitin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 细胞定位
    [Ubiquitin]: Cytoplasm. Nucleus
  • 功能
    [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell- cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored- polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
储存与保存
1.保存：-20℃
2.有效期：1年
注意事项
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。

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