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Claudin 3 (17X5) Rabbit Monoclonal Antibody  Cite:0    分享
抗体类满2送1  

货号： IM33437
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  • 种属：H，M，R
  • 用途：WB，ELISA，IP，IHC-P，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Claudin 3 (17X5) Rabbit Monoclonal Antibody
  • 别名
    C7orf1;Claudin-3;Claudin3;CLD3_HUMAN;CLDN 3;Cldn3;Clostridium perfringens enterotoxin receptor 2;CPE R2;CPE receptor 2;CPE-R 2;CPE-receptor 2;CPETR 2;CPETR2;HRVP 1;HRVP1;Rat ventral prostate 1 like protein;Rat ventral prostate.1 protein homolog;RVP1;Ventral prostate.1 like protein;Ventral prostate.1 protein homolog;C7orf1;CPETR2
  • 类别
    抗体产品
  • 基因名称
    CLDN3
  • 蛋白名称
    C7orf1;Claudin-3;Claudin3;CLD3_HUMAN;CLDN 3;Cldn3;Clostridium perfringens enterotoxin receptor 2;CPE R2;CPE receptor 2;CPE-R 2;CPE-receptor 2;CPETR 2;CPETR2;HRVP 1;HRVP1;Rat ventral prostate 1 like protein;Rat ventral prostate.1 protein homolog;RVP1;Ventral prostate.1 like protein;Ventral prostate.1 protein homolog
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
  • 稀释度
    IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    1365
  • Human Swissprot No.
    O15551
  • Mouse Swissprot No.
    Q9Z0G9
  • Rat Swissprot No.
    Q63400
  • 特异性
    Endogenous
  • 参考分子量
    20kDa
  • 预测分子量
    23kDa
  • 宿主
    Rabbit
  • 同种型
    IgG,Kappa
  • 背景介绍
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008],
  • 组织表达
    Colon/ Appendix
  • 细胞定位
    Membranous
  • 功能
    Disease:Haploinsufficiency of CLDN3 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,Function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
  • 纯化
    Protein A
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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