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PI3 Kinase p85 beta (4G3) Rabbit Monoclonal Antibody  Cite:0    分享
抗体类满2送1  

货号： IM30818
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  • 种属：H，R
  • 用途：WB，FCM，IP，IHC-P，IF-P，IF-F，IF-ICC，IHC-F
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    PI3 Kinase p85 beta (4G3) Rabbit Monoclonal Antibody
  • 别名
    p85; p85 beta; P85B; Phosphatidylinositol 3 kinase; PI3 kinase p85 beta subunit; PI3K; PIK3R 2;
  • 类别
    抗体产品
  • 基因名称
    PIK3R2
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IHC-F,IF-ICC,IF-P,IF-F,IP,FCM
  • 稀释度
    WB 1:1000-1:2000,IHC-P/IHC-F 1:100-1:200,IF-ICC 1:50-1:200,IF-P/IF-F 1:50-1:200,IP 1:20-1:50,FCM 1:20-1:100
  • 反应种属
    Human,Rat
  • 存储缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Human Gene ID
    5296
  • Human Swissprot No.
    O00459
  • 参考分子量
    82kDa
  • 预测分子量
    82kDa
  • 功能
    Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5- bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein- tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin- dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
  • 纯化
    Affinity-chromatography
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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