热搜词： 生化试剂 血清抗 细胞 pvdf膜 抗体

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Anti-PRKACA Polyclonal Antibody  Cite:0    分享

货号： IM72007
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  • 种属：H，M，R
  • 用途：WB，IHC
规格:
50μl 100μl
单位:
支
单价:￥1400.00
产品简介
储存与保存
注意事项
产品简介
  • 货号
    IM72007
  • 产品名称
    Anti-PRKACA Polyclonal Antibody
  • 宿主
    Rabbit
  • 克隆类型
    Polyclonal Antibody
  • 亚型
    IgG
  • 交叉反应
    Human ; Rat ; Mouse
  • 应用
    IHC ; WB
  • 稀释比例
    WB 1:200-1000. IHC 1:25-100
  • 靶标
    PRKACA
  • 别名
    PPKACA;PKACA;PPNAD4;PKA C-alph
  • 背景说明
    This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Swiss Prot
    P17612
  • Gene ID
    5566
  • 亚细胞定位
    Cell membrane Cell projection Cytoplasm Lipid-anchor Membrane Mitochondrion Nucleus cilium flagellum
  • 免疫原
    A synthetic peptide of human PRKACA
  • 理论分子量
    41kDa
  • 纯化方法
    Affinity purification
  • 储存液
    pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存与保存

Store at -20℃. Avoid freeze/thaw cycles.

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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