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CD206/MRC1 (10G17) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM72004
复制产品信息
  • 种属：H，M，R
  • 用途：WB，ELISA，IP，IHC-P，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 货号
    IM72004
  • 别名
    MRC1;CLEC13D;CLEC13DL;MRC1L1;Macrophage mannose receptor 1;MMR;C-type lectin domain family 13 member D;C-type lectin domain family 13 member D-like;Macrophage mannose receptor 1-like protein 1;CD206
  • 产品名称
    CD206/MRC1 (10G17) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    MRC1
  • 蛋白名称
    Macrophage mannose receptor 1
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 同源性
    Macaca fascicularis（98.01%）
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    4360
  • Human Swissprot No.
    P22897
  • Mouse Gene ID
    17533
  • Mouse Swissprot No.
    Q61830
  • 特异性
    Endogenous
  • 稀释度
    HC-P 1:200-1:1000, WB 1:5000-1:20000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
  • 参考分子量
    190kDa
  • 预测分子量
    190kDa
  • 宿主
    Rabbit
  • 同种型
    IgG,Kappa
  • 背景介绍
    The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015],
  • 组织表达
    Milk,Placenta,Testis,
  • 细胞定位
    Membrane
  • 功能
    Function:Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.,miscellaneous:CRDs 1-3 have at most very weak affinity for carbohydrate. CRD 4 shows the highest affinity binding and has multispecificity for a variety of monosaccharides. At least 3 CRDs (4, 5, and 7) are required for high affinity binding and endocytosis of multivalent glycoconjugates.,online information:Macrophage mannose receptor,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 ricin B-type lectin domain.,similarity:Contains 8 C-type lectin domains.,
  • 纯化
    Protein A
储存与保存

1.保存：-20℃
2.有效期：1年

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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