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Osteopontin (6P8) Rabbit Monoclonal Antibody  Cite:0    分享
抗体类满2送1  

货号: IM68735
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IP,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
支
单价:¥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM68735
  • 别名
    SPP1;BNSP;OPN;PSEC0156;Osteopontin;Bone sialoprotein 1;Nephropontin;Secreted phosphoprotein 1;SPP-1;Urinary stone protein;Uropontin
  • 产品名称
    Osteopontin (6P8) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    SPP1
  • 蛋白名称
    Osteopontin
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    6696
  • Human Swissprot No.
    P10451
  • Mouse Gene ID
    20750
  • Mouse Swissprot No.
    P10923
  • Rat Gene ID
    25353
  • Rat Swissprot No.
    P08721
  • 稀释度
    IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
  • 参考分子量
    55,65kDa
  • 预测分子量
    35kDa
  • 宿主
    Rabbit
  • 同种型
    Monoclonal, rabbit, IgG, Kappa
  • 背景介绍
    secreted phosphoprotein 1(SPP1) Homo sapiens The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
  • 信号通路
    Focal adhesion;ECM-receptor interaction;Toll_Like
  • 功能
    disease:This protein plays a principal role in urinary stone formation as the stone matrix.,function:Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.,function:Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.,online information:Osteopontin entry,PTM:Extensively phosphorylated on clustered serine residues.,PTM:N- and O-glycosylated.,similarity:Belongs to the osteopontin family.,subunit:Ligand for integrin alpha-V/beta-3.
  • 纯化
    Protein A
  • Clonality
    Monoclonal
储存与保存

1.保存:-20℃

2.有效期:1年

注意事项

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