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Beclin 1 (14P2) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM68680
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IP,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM68680
  • 别名
    Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197);GT197
  • 产品名称
    Beclin 1 (14P2) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    BECN1
  • 蛋白名称
    Beclin-1 (Ser15)
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    8678
  • Human Swissprot No.
    Q14457
  • Mouse Gene ID
    56208
  • Mouse Swissprot No.
    O88597
  • Rat Gene ID
    114558
  • Rat Swissprot No.
    Q91XJ1
  • 稀释度
    IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
  • 参考分子量
    60kDa
  • 预测分子量
    52kDa
  • 宿主
    Rabbit
  • 同种型
    Monoclonal, rabbit, IgG, Kappa
  • 背景介绍
    beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].
  • 信号通路
    Regulation of autophagy
  • 功能
    function:Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.,similarity:Belongs to the beclin family.,subcellular location:Expressed in dendrites and cell bodies of cerebellar Purkinje cells.,subunit:Interacts with GOPC and GRID2. Interacts with AMBRA1. Probably forms a complex with AMBRA1 and PIK3C3 (By similarity). Interacts with BCL2 and BCL2L1.,tissue specificity:Ubiquitous.
  • 纯化
    Protein A
储存与保存

1.保存:-20℃

2.有效期:1年

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