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VASP (Phospho S156) (13H19) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM37145
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  • 种属：H
  • 用途：WB，IP
规格:
50µl 100µl
单位:
支
单价:￥1200.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM37145
  • 纯度
    Affinity-chromatography
  • 别名
    Vasodilator stimulated phosphoprotein; VASP
  • 产品名称
    VASP (Phospho S156) (13H19) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    VASP
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IP
  • 反应种属
    Human
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID
    7408
  • Human Swissprot No.
    P50552
  • 免疫原
    A synthetic phosphopeptide corresponding to residues surrounding Ser239 of human VASP
  • 稀释度
    WB 1:1000, IP 1:20-1:50
  • 参考分子量
    48kDa
  • 预测分子量
    40kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 注意事项
    Phospho-VASP (S156) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 组织表达
    Highly expressed in platelets.
  • 细胞定位
    Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction Cell projection, lamellipodium membrane. Cell projection, filopodium membrane. Note=Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions. Localized along the sides of actin filaments throughout the peripheral cytoplasm under basal conditions. In pre- apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes).
  • 功能
    Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
储存与保存

Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles.

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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