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GLUT4 (Phospho S488) (19E6) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM37136
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  • 种属：H，M，R
  • 用途：WB
规格:
50µl 100µl
单位:
支
单价:￥1200.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM37136
  • 纯度
    Affinity-chromatography
  • 别名
    insulin-responsive; Glucose transporter GLUT 4; Glucose transporter type 4; Glucose transporter type 4 insulin responsive; GLUT4; Insulin responsive glucose transporter type 4; SLC2A4 ; Solute carrier family 2 member 4.
  • 产品名称
    GLUT4 (Phospho S488) (19E6) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    SLC2A4
  • Clonality
    Monoclonal
  • 推荐应用
    WB
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Human Gene ID
    6517
  • Human Swissprot No.
    P14672
  • 稀释度
    WB 1:1000-1:2000
  • 参考分子量
    45kDa
  • 预测分子量
    55kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 注意事项
    Phospho-GLUT4 (S488) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 组织表达
    Skeletal and cardiac muscles; brown and white fat.
  • 细胞定位
    Cell membrane {ECO:0000250|UniProtKB:P14142}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P14142} Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P14142}. Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized (PubMed:8300557). The dileucine internalization motif is critical for intracellular sequestration (PubMed:8300557). Insulin stimulation induces translocation to the cell membrane (By similarity) {ECO:0000250|UniProtKB:P14142, ECO:0000269|PubMed:8300557}
  • 功能
    Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
储存与保存

Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles.

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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