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EDG-5 Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM53281
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
支
单价:¥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    EDG-5 Rabbit Polyclonal Antibody
  • 别名
    S1PR2; EDG5; Sphingosine 1-phosphate receptor 2; S1P receptor 2; S1P2; Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5
  • 类别
    抗体产品
  • 基因名称
    S1PR2
  • 蛋白名称
    Sphingosine 1-phosphate receptor 2
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-1:2000, IHC-P 1:100-1:300, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:10000.Not yet tested in other applications.
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    9294
  • Human Swissprot No.
    O95136
  • Mouse Gene ID
    14739
  • Mouse Swissprot No.
    P52592
  • Rat Gene ID
    29415
  • Rat Swissprot No.
    P47752
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human EDG5. AA range:261-310
  • 特异性
    EDG-5 Polyclonal Antibody detects endogenous levels of EDG-5 protein.
  • 预测分子量
    39kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016],
  • 组织表达
    Fetal brain
  • 细胞定位
    Cell membrane; Multi-pass membrane protein.
  • 信号通路
    Neuroactive ligand-receptor interaction
  • 功能
    function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.,similarity:Belongs to the G-protein coupled receptor 1 family.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存:-20℃,Avoid freeze/thaw cycles

2.有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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