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CREB-1 Rabbit pAb  Cite:0    分享

货号： IM52957
复制产品信息
  • 种属：H，M，R
  • 用途：WB，Flow Cyt
规格:
50μl 100μl
单位:
支
单价:￥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 货号
    IM52957
  • 产品名称
    CREB-1 Rabbit pAb
  • 英文别名
    CREB; CREB-1; 2310001E10Rik; 3526402H21Rik; CREB1_BOVIN; CREB1; cAMP-responsive element-binding protein 1; Cyclic AMP-responsive DNA-binding protein; CREB2; CREB1_HUMAN; CREB1_MOUSE; CREB1_RAT;
  • 产品应用
    WB、Flow-Cyt
  • 交叉反应
    Human, Mouse, Rat
  • 推荐稀释比例
    WB:1:500-2000 、Flow-Cyt:1μg/Test
  • 抗体来源
    Rabbit
  • 免疫原
    KLH conjugated synthetic peptide derived from human CREB-1 : 51-120/341
  • 亚型
    IgG
  • 性状
    Liquid
  • 纯化方法
    affinity purified by Protein A
  • 克隆类型
    Polyclonal
  • 理论分子量
    37 kDa
  • 浓度
    1mg/ml
  • 储存液
    0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
  • 研究领域
    Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > HLH / Leucine Zipper Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Immunology > Innate Immunity > TLR Signaling
  • SWISS
    P16220
  • Gene ID
    1385
  • 背景资料
    The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, ATF-1,ATF-2,ATF-3and ATF-4. these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, in cerain instances they also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), which may reprecent a CREB co-activator.
储存与保存

1.保存：-20℃
2.有效期：1年

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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