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Beclin-1 (Phospho Ser93/96) Rabbit Polyclonal Antibody  Cite:0    分享
抗体类满2送1  

货号: IM68542
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  • 种属:H,M,R
  • 用途:WB,IHC-P
规格:
50μl 100μl
单位:
单价:¥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Beclin-1 (Phospho Ser93/96) Rabbit Polyclonal Antibody
  • 别名
    Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197);GT197
  • 类别
    抗体产品
  • 基因名称
    BECN1
  • 蛋白名称
    Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)
  • Clonality
    Polyclonal
  • 推荐应用
    IHC-P,WB
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 制备方法
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
  • Human Gene ID
    8678
  • Human Swissprot No.
    Q14457
  • Mouse Gene ID
    56208
  • Mouse Swissprot No.
    O88597
  • Rat Gene ID
    114558
  • Rat Swissprot No.
    Q91XJ1
  • 特异性
    This antibody detects endogenous levels of Beclin-1 (Phospho Ser93/96) Rabbit pAb at Human, Mouse,Rat
  • 稀释度
    WB 1:500-2000, IHC-P 1:50-200
  • 参考分子量
    55kDa
  • 序列
    Q14457
  • 组织表达
    Ubiquitous
  • 细胞定位
    Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .
  • 功能
    function:Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.,similarity:Belongs to the beclin family.,subcellular location:Expressed in dendrites and cell bodies of cerebellar Purkinje cells.,subunit:Interacts with GOPC and GRID2. Interacts with AMBRA1. Probably forms a complex with AMBRA1 and PIK3C3 (By similarity). Interacts with BCL2 and BCL2L1.,tissue specificity:Ubiquitous.,
储存与保存

1. 保存:-20℃,Avoid freeze/thaw cycles
2. 有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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