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抗体蛋白
二抗生物素标记 过氧化物酶(HRP)标记 胶体金试剂 FITC荧光标记 RBITC荧光标记 二抗免疫血清 其它荧光标记二抗 藻红蛋白(PE)荧光标记 胶体金(Gold)标记 SAlexa Fluor荧光系列 碱性磷酸酶(AP)标记 别藻蓝蛋白(APC)荧光标记 其它标记 PE标记二抗 DyLight标记二抗 AU标记二抗 Biotin标记二抗 AMCA标记二抗 Texas Red标记二抗 TRITC标记二抗 HRP标记二抗 未标记二抗 Cy标记二抗 AbBox Fluor标记二抗内参抗体 小分子抗体抗体标记试剂盒细菌抗体蛋白病毒包装试剂杂交瘤融合筛选WB、IHC、ELISA相关试剂细胞培养试剂病原微生物抗原抗体假病毒抗体校准品其他抗原抗体标记的标签抗体病理级IHC抗体重组蛋白
- 细胞培养
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斑马鱼产品
订货方式
订货电话：13564444959
订货时间：周一至周五
订货Q Q：79688691
订货邮件：79688691@qq.com
订货时间：周一至周五
订货Q Q：79688691
订货邮件：79688691@qq.com
产品简介
储存与保存
注意事项
产品简介-
货号IM48672
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别名MCT1
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产品名称MOT1 Rabbit Polyclonal Antibody
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类别抗体产品
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基因名称SLC16A1
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蛋白名称Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1)
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ClonalityPolyclonal
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推荐应用WB,ELISA
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反应种属Human,Rat,Mouse
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浓度1 mg/ml
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存储缓冲液Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
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Human Gene ID6566
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Human Swissprot No.P53985
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Mouse Swissprot No.P53986
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Rat Swissprot No.P53987
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免疫原Synthesized peptide derived from human protein . at AA range: 240-320
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特异性MOT1 Polyclonal Antibody detects endogenous levels of protein.
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稀释度WB 1:500-2000, ELISA 1:5000-20000
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预测分子量55kDa
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宿主Rabbit
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同种型Rabbit,IgG
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背景介绍The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009],
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组织表达Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed.
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细胞定位Cell membrane ; Multi-pass membrane protein .
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功能disease:Defects in SLC16A1 are the cause of familial hyperinsulinemic hypoglycemia type 7 (HHF7) [MIM:610021]; also known as exercise-induced hyperinsulinemic hypoglycemia. HHF7 is a dominantly inherited hypoglycemic disorder characterized by inappropriate insulin secretion during anaerobic exercise or on pyruvate load.,disease:Defects in SLC16A1 are the cause of symptomatic deficiency in lactate transport (SDLT) [MIM:245340]; also known as erythrocyte lactate transporter defect. Deficiency of lactate transporter may result in an acidic intracellular environment created by muscle activity with consequent degeneration of muscle and release of myoglobin and creatine kinase. This defect might compromise extreme performance in otherwise healthy individuals.,function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Widely expressed in normal and in cancer cells.,
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纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存1.保存：-20℃
2.有效期：1年
注意事项1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
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